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BioProtein Plus is a breakthrough immune boosting formulated supplement used by thousands of people in the United States
and around the world to strengthen and improve immune system function
and live healthier lives.
BioProtein+ Plus also refered to as (BioPro) contains biologically active purified thymic proteins ranging from 10,000 to 50,000 Dalton's plus
100mcg of thymic protein and 1mg zinc gluconate freeze-dried in a base of Maltodextrin.
It is a specially formulated thymus supplement that is designed to
support and improve immune system function. The thymus gland plays a key
role in the immune system by releasing proteins that program white
blood cells to resist invading pathogens.
Thymus proteins exist
naturally in the body and play an essential role in the immune system by
programming special disease-fighting cells called T-lymphocytes.
T-lymphocytes are white blood cells and are the immune system’s main
defense against infections.
By harnessing the immune boosting power of
thymus proteins, BioProtein Plus has quickly become the premier immune
system supplement on the market. BioProtein-Plus also contains Zinc
Gluconate, another powerful immune boosting supplement.
The calf thymus
used in its manufacture comes from dairies in the US that only produce
certified raw dairy products. It is certified free of microorganisms and
BSE. The proteins are purified efficiently by the most up to date assay
techniques while taking great care to maintain the proteins’ biological
activity. They are then lyophilized to maintain their long-term
stability. BioProtein Plus is packaged in the USA in an FDA approved
packaging facility.
BioProtein+Plus has been used for Immune Support, Colds, Flu, Hepatitis
C, and other Viral Infections. Results reported by customers may reduce
the side effects of Chemotherapy and Radiation treatment for cancer.
BioProtein+Plus is undergoing clinical trials for the treatment of Hepatitis C, Chemotherapy Toxicity, and immune disorders.
Suggested Dosage:
INITIAL DOSE; at the first symptoms or in midst of severe infection,
administer 1 sub-lingual packet of BIOPROTEIN+PLUS every hour over a 5
to 7 hour period (5-7 x), and repeat this regimen for one (1) to three
(3) days.
SUBSEQUENT DOSE; continue with 3 packets per day of BIOPROTEIN+PLUS for an additional 3-4 days or until symptoms subside.
MAINTENANCE DOSE; a single packet per day of sub-lingual
BIOPROTEIN+PLUS as a maintenance dose, may sustain the immune response
and anyone that is high risk for respiratory disease, or works as a
health care professional in an infectious environment should stay on
this dosage daily to maintain the highest level of wellness attainable.
FAQ BioProtein+PlusTM
Unique Thymic Compound
Q: What is BioProtein+PlusTM?
A: BioProtein+Plus is a specially formulated supplement designed to support healthy immune system function.
Q: What is BioProtein+Plus that helps immune system function?
A:The thymus gland plays a key
role in the immune system by releasing proteins that program white
blood cells to resist invading pathogens.
BioProtein+Plus contains Purified Thymus Proteins and Zinc Gluconate
freeze-dried in a base of Maltodextrin. Each packet contains 100mcg of
thymic protein and 1mg zinc gluconate.
Q: What are Purified Thymus Protein?
A: Purified Thymus Proteins are proteins separated from thymus gland
tissue by a gentle biological technique to keep them in their natural
active state, just as they exist in the body (biologically active).
Thymus proteins exist
naturally in the body and play an essential role in the immune system by
programming special disease-fighting cells called T-lymphocytes.
T-lymphocytes are white blood cells and are the immune system’s main
defense against infections.
Q: What is the job of a Thymus Protein?
A: Thymus Protein come from the Thymus gland, a small ductless gland
under the breast bone. Their job is to program specific white blood
cells called T-lymphocytes.
Q: And the job of T-lymphocytes?
A: T-lymphocytes or T=cells are cells that specialize in suppressing virus and cancer.
Q: Why take a thymus supplement when I already have a thymus gland?
A: A person's thymus gland becomes less active with age, stress,
disease or trauma and can leave a person vulnerable to illness because
of the lack of production of thymus proteins. Supplementing with
biologically active thymus proteins helps, as proven in a number of
clinical trials.
Q: Why is Zinc Gluconate in BioProtein+Plus, can't I get too much Zinc?
A: BioProtein+Plus contains Purified Thymus Proteins and Zinc
Gluconate. Zinc Gluconate helps the Purified Thymus Proteins interact
with the T-cells. Zinc Gluconate by itself is clinically proven to
reduce the duration of the common cold. The amount of Zinc in each dose
is not high enough to cause toxicity even in a person who takes a
separate Zinc supplement.
Q:Who should take BioProtein+Plus?
A: As with all supplements, a person should get professional advice.
BioProtein+Plus has been used successfully by men, women and children of
all ages.
*Not recommended for pregnant women.
Q: For what is BioProtein+Plus most commonly used?
A: To promote overall good health. Prevention of and reducing the
duration of cold and flu symptoms. Before and after surgery. Before,
during and after chemotherapy and/or radiation treatment. In conjunction
with an Anti-Aging regimen.
Q: Are there any clinical trials?
A: BioProtein+Plus has been shown to help reduce levels of harmful liver enzymes and virus levels in people with Hepatitis C.
BioProtein+Plus - Biologically Active Thymus Proteins plus Zinc Balances Immune System Function
By, Daniel Clark M.D.
Immune Dysfunction
Dysfunction of the Immune System affects about 65 million Americans.
These dysfunctions manifest themselves in disorders such as Chronic
Allergies and Respiratory problems, Arthritis, Diabetes, Lupus
Erythematosus and Chronic Viral infections to name a few. The cost in
terms of lost time at work, cost of related health care and diminished
quality of life cannot be accurately estimated. However, everyone agrees
that the costs are enormous. A good deal of the time and money related
to Immune Dysfunction is actually spent treating the disorders rather
than directly approaching the underlying cause itself.
Immune Dysfunction is likely the result of a combination of assaults on
the immune system. Generally there is immune suppression, then
infection followed by treatment of the infection. If immune function is
not restored, the initial infection may not resolve, or it may be
followed by another infection eventually overwhelming the immune system
causing it to overreact and under-react simultaneously. This is classic
Immune Dysfunction, a patient with multiple low-grade infections and
autoimmune disorders at the same time. Direct immune stimulation may
exacerbate the autoimmune disorders, while treating autoimmune disorders
may suppress immunity and allow infection to proliferate.
The Thymus Gland
The "brain" of the immune system is the thymus gland. It lies just
beneath the breastbone and is responsible for producing perhaps dozens
of different polypeptides that "program" lymphocyte progenitors.
Lymphocytes are born in the bone marrow; some receive their programming
in the bone marrow and are referred to as B-lymphocytes. Others migrate
to the thymus gland to mature by contacting the thymic proteins and are
referred to as T-lymphocytes. The T-lymphocytes display receptor sites
on their surface that correspond to transmitter sites on the surface of
the various thymic proteins. When the appropriate T-lymphocyte contacts
its corresponding protein, the transmitter fits into the receptor (much
like a key fits into a lock) and the lymphocyte is now ready to perform
its specific function or is otherwise immune-competent.
There are two main types of T-lymphocytes. These are the T-4 (CD4)
helper, and the T-8 (CD8) that further differentiate into killer and
suppressor types. Helper cells not only induce killer and suppressor
cells but also induce B-lymphocytes, and macrophages. Killer cells do
just that, kill. When they are immune-competent they have the ability to
recognize deviant cells such as tumor cells and the body's own cells
that are virally infected. Once recognized, the killer cell attacks.
Sometimes killer cells overreact by attacking self-tissue (auto-immune
disease) but if immune-competent suppressor cells are present, they
intervene and stop the attack. Thus when the system is functioning
properly the thymus produces proteins that "program" T-lymphocytes that
start and stop immune response. Due to genetic flaw, trauma, stress,
disease, exposure to toxic substances and/or inevitably the aging
process, the thymus ceases to produce its proteins in the proper
quantity or combination's to maintain immune balance.
Supplementation with Thymic Proteins
The use of thymic extracts has been well studied. There is a
substantial body of clinical evidence that indicates the use of thymus
is effective in the treatment of a number of diseases and disorders.
Chronic viral infections, different types of cancers, and some
auto-immune disorders are a few that I will discuss here.
Double-blind studies reveal that thymus extracts are able to eliminate
viral infection; and continued use over one year reduces the number of
recurrent infections. Additionally, patients in the studies show
improved immune parameters. In cancer patients, the primary indication
for thymus use is for the treatment of lymphopenia/leukopenia caused by
chemotherapy and radiation treatments. The effect is to prevent or at
least mitigate the dramatic drop in white blood cell levels and to
restore counts more quickly in cases where they do drop. The net result
of patients taking thymus are that they are more often able to complete
their treatment and with reduced side effects than in patients who do
not take thumus
2,3. Autoimmune disorders are immune dysfunction where the bodies' own defense mechanisms are attacking self-tissue.
Rheumatoid Arthritis, Lupus, and Scleroderma are classic disorders
caused by increased antibody formation brought on by a high
T-helper/T-suppressor ratio. A clinical study in Rheumatoid Arthritis
patients revealed that thymus extract use normalized their
T-helper/T-suppressor ratios in three months
2. Thymus is
also indicated for the treatment of Hepatitis C, AIDS, Chronic Fatigue,
Cold and Flu, Lupus Erythematosis, Type II Diabetes and Scleroderma.
Studies are presently being conducted for the treatment of Hepatitis C.
Another area of recent study for the application of thymus products has
to do with the role lymphocytes play in periodontal disease. The first
line of defense against bacterial plaque is neutrophils. Neutrophils are
depressed in people susceptible to periodontal disease such as
diabetics and the geriatric population. Lymphocytes promote neutrophil
growth and thymus proteins promote lymphocyte growth. Lymphocytes
therefore play a major role in prevention and resolution of periodontal
disease
10,11.
Volumes of scientific data exist now to support the use of thymus
products for immune suppression and immune dysfunction. There is
precious little data however suggesting which specific thymus product is
most effective.
Which Thymus Products are Best?
There are a variety of thymus products available from raw thymus tissue
to highly purified thymus proteins and many thymus extracts in between.
Thymus proteins are produced in the thymic epithelium and range in size
from probably around 10,000 Dalton to perhaps over 50,000 Dalton.
Whether large or small, proteins are complex molecules that can be
easily damaged (de-natured) or changed. Changes in the protein molecule
can bear directly on its biological activity and therefore its ability
to "program" T-lymphocytes.
Therefore the manner in which the thymus product is handled and
administered will bear directly upon how much benefit the patient
experiences from using it.
Typical thymic extracts are composed of ground up thymus tissue, which
is then freeze-dried and encapsulated to be swallowed and absorbed in
the gastrointestinal tract. There are also liquid thymus extract drops
that are taken sublingually and a few products of freeze-dried purified
thymus protein that is also administered sublingually.
My experience has taught me that the purified thymus protein
administered sublingually is the most effective. I have recently been
testing a thymic compound called BioProtein+PlusTM that contains
purified biologically active thymus proteins ranging in atomic size from
10,000 to 50,000 Dalton plus Zinc Gluconate.
The Role of Zinc
DNA makes RNA, which in turn makes proteins. Proteins drive biological
function. Trace minerals work as catalysts or activators in enzyme
complexes and influence reactivity and stability of protein
configurations. Zinc has anti-oxidant properties and serves a vital role
in many immune functions. Studies have shown that Zinc must be present
for lymphocyte maturation and is a lymphocyte mitogen. Additionally,
zinc is a necessary co-factor in activation of serum thymic factor5,6.
Zinc Gluconate has been clinically proven to reduce the duration of the
common cold by an average of 7 days
7,8.
Zinc may also have some anti-aging benefits. An important study of zinc
supplementation in elderly patients resulted in increased numbers of
T-cells and enhanced cell-mediated immune responses
9.
Our testing indicates that BioProtein+PlusTM works to regulate the
T-helper/T-killer/T-suppressor interaction resulting in normalization of
immune response. Our experience is consistent with clinical studies
conducted with other thymus products. The quality of our results are due
to the combination of biologically active purified thymus proteins
contained in BioProtein+PlusTM working synergistically with the zinc
gluconate to induce immune regulation.
A Unique Thymic Compound
BioProtein+PlusTM is a
proprietary formula produced by the original manufacturer of BioPro
Thymic Protein A. The thymus used in its manufacture comes from dairies
in the US that only produce certified raw dairy products. It is
certified free of microorganisms and BSE. The proteins are purified
efficiently by the most up to date assay techniques while taking great
care to maintain the proteins' biological activity. They are then
lyophilized to maintain their long-term stability.
The zinc gluconate used in the manufacture of BioProtein+PlusTM is of
the highest quality available. Once freeze-dried, the purified thymus
proteins and the zinc gluconate are triturated into a base of
maltodextrin and packaged in doses containing
100mcg of thymic proteins and 1mg zinc gluconate
.
It is recommended by the manufacturer to be taken as a once per day
supplement. Just as with BioPro Thymic Protein A, we have not seen any
adverse side effects. On some occasions a health care professional may
recommend more than one per day. As with other zinc products, toxicity
does not occur unless a person takes over 150 mg of zinc per day for
more than two weeks. BioProtein+PlusTM contains 1 mg of zinc per dose.
There are no known contraindications but
BioProtein+PlusTM is likely to be less effective for people using steroidal medications.
Clinical Observations
As of this writing two clinical trials have begun using BioProtein+Plus
TM. One trial is being conducted on subjects with Hepatitis C, the end
point being to reduce viral load, normalize ALT, AST and increase
general well being. The second trial is on Lymphopenia caused by
chemotherapy toxicity. The following are observations made of
individuals from these two trials:
Hepatitis C
As of mid-September 2001, there are 30 patients enrolled in an open
label study. All are positive Hepatitis C patients with no co-infection
and no other therapy. In the first 4-8 weeks taking one packet per day,
26 patients report feeling better and 20 have shown positive clinical
improvement by blood parameters.
Chemotherapy Toxicity
Ethel began Taxol treatment for breast cancer in December 1999. She
began using three packets of BioProtein+Plus TM per day when she began
treatment. As of mid-July, 2000 she has received 8 rounds of Taxol.
Throughout her treatment her blood parameters have remained in the
normal range except her lymphocyte count dropped below normal for six
weeks from mid-March to the end of April. She completed her Taxol
treatment without interruption.
Brief reports from health care professionals:
Kathryn, an acupuncturist in the state of Florida, has found the new
BioProtein+Plus to be very effective at reducing viral load on her
Hepatitis C patients referred to her by an Internist for acupuncture
treatments.
Michael, an acupuncturist also in the state of Florida, has found the
new BioProtein+Plus effective in balancing immune function for a number
of patients with autoimmune disorders.
Denise and Luby Chambul, D.C. of Nashville, Tennessee have used the
BioProtein+Plus in Hepatitis C patients with effective reduction of
viral load.
Dr. Warren : I have been dispensing BioPro Thymic Protein A for over 4
years, to clients with a variety of health problems ranging form simple
immune dysfunction to severe debilitating diseases like; Chronic
Fatigue, Hepatitis C, severe Lymphopenia, and Cancer. In the vast
majority of cases (90%), I have seen positive health benefits when the
product was taken as recommended.
Since being introduced to the "new generation" product,
BioProtein+Plus, I have observed the same extraordinary health benefits
previously experienced with the aforementioned product and in several
cases a more natural or complete immune regulation response has been
observed, with out the "inflammatory flare" sometimes seen with BioPro. I
can only surmise this is because of the more balanced and complete
formulation of purified thymus proteins coupled with the zinc found in
BioProtein+Plus.
I feel both products are phenomenal in enhancing the immune response,
however, because of the smooth immune modulation and the cost
differential between the two products, I prefer BioProtein+plus, as the
supplement of choice to fully restore the cell mediated immunity so
necessary for a healthy life.
Conclusion
Nothing teaches and convinces like one's own experience. The author's
own observations and experience as well as other health care
professionals is that BioProtein+PlusTM is an excellent tool in the
battle against immune dysfunction.
NOTE:
If you are a person who suffers with chronic viral infection while at
the same time dealing with autoimmune disorder, ask your health
professional about this product. If you are a health professional
looking for an effective and cost-effective tool to recommend to your
clients, consider trying this product and experience for yourself the
benefits.
Thymus Gland, Its Function and How Thymic Peptides Work
The thymus gland is a ductless gland which lies just beneath the
breastbone. It is almost non-existent in adults due to rapid atrophy
after adolescence. Because it is so small in adults, it was long thought
to be of little importance until its true function was discovered in
1960. One technique researchers used to discover the function of the
thymus was to remove it from young animals and study the resultant
changes.
When small animals have their thymus removed (thymectomy), they
experience a profound "wasting disease". The wasting syndrome is
characterized by an increased incidence of infection and cancer (immune
suppression, failure to grow, allergies, neuromuscular paralysis , and
auto immune diseases (immune dysfunction). Greater susceptibility to
infection and cancer was shown to be directly attributable to a dramatic
decrease in peripheral blood lymphocytes (lymphopenia). Rearing the
animal in a sterile environment prevented the increased incidence of
infection and cancer but did not eliminate all of the symptoms caused by
thymectomy.
In 1964 it was demonstrated that hormone-like factors from thymus tissue
could prevent many of the manifestations of the wasting syndrome caused
by thymectomy. This research suggested that the thymus gland produces
substances that are important to the development of the immune system.
Although the relationship of this observation and the other wasting
syndrome symptoms were not yet understood, the importance of the thymus
gland was beginning to be revealed.
Once it was discovered that the thymus produces these hormone-like
factors, several groups of scientists began trying to extract and purify
the material from thymus glands or serum. The model for this research
was the preparation of insulin for therapeutic use in diabetes. Since
the thymus produces extremely small quantities of the factors,
researchers require large numbers of thymus glands or liters of serum to
biochemically extract small amounts of active materials. This approach
was met with limited success.
This research brought forth Thymosin in 1967 the first of many peptides
(small protein fragments) to be extracted and extensively studied.
Thymosin fraction V is from bovine thymus and is a mixture of thirty or
more peptides. An active component, one which had biological activity
was isolated from this mixture. It is a 28 amino acid fragment of the
extract called Thymosin Alpha 1. It displayed a variety of immune
stimulatory properties in the laboratory, and has been useful clinically
as a treatment for hepatitis B in combination with alpha-interferon.
References
- Riocchi A, Borella E, Riva E. et al. A double blind clinical
trial for the evaluation of the therapeutic effectiveness of a calf
thymus derivative in children with recurrent repiratory infection.
Thymus 1986; 8: 831-839.
- Kouttab NM, Prada M., Cazzola P. Thymomodulim. Biological
properties and clinical applications. Med Oncol Tumor Pharmacother 1989;
6: 5-9.
- Kang SD, Lee B H, Yand JH, Lee CY. The effects of calf-thymus
extract on recovery of bone marrow function in anticancer chemotherapy.
New Med J (Korea) 1985; 28: 11-15.
- Cazzola P, Mazzanti P, Bossi G. In vivo modulation effect of a
calf thymus acid lysate on human T Lymphocyte subsets and CD4+/CD8+
ratio in the course of different diseases. Curr Ther Res 1987; 42:
1011-1017.
- Eaterbrook-Smith S. Activation of the binding of C1q to immune complexes by zinc. FEBS Lett 1983; 162: 117-119.
- Hadden JW. The treatment of zinc deficiency is an immunotherapy. Int J Immunopharmac 1995; 17: 697-701.
- Eby GA, Davis DR, Halcomb WW. Reduction in duration of common
colds by zinc gluconate lozenges in a double-blind study. Antimicrob
Agents Chemother 1984; 25: 20-24.
- Mossad SB, Macnin ML, Medendorp SV et al. Zinc gluconate lozenges
for treating the common cold. A randomized, double blind,
placebo-controlled study. Annals Intern Med 1996; 125: 81-88.
- Gershwin M, beach R, Hurley L. Trace metals, aging and immunity. J Am Ger Soc 1983; 31: 374-378.
- Carranza F. Glickman's clinical peridontology. Philadelphia, PA: WB Saunders. 1984.
- Page R, Schroeder H. Current status of the host response in chronic marginal periodontis. J Periodontal 1981; 53: 477-491.
*These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure,
or prevent any disease.
Suggested Dosage
INITIAL DOSE - at the first sign of or in the midst of severe
infection, take 1 packet of BioProtein+Plus
every hour over a 5 to 7 hour period (5-7 x), and repeat regimen for one to
three days.
SUBSEQUENT DOSE
- continue with 3 packets
per day of BioProtein+Plus for an additional 3-4days or until
symptoms subside.
MAINTENANCE
DOSE - a single packet per day will sustain the immune response and
anyone that is high risk for respiratory disease, or works as a health care
professional in an infectious environment should
stay on this dosage daily
to maintain the highest
level of wellness attainable.
NOTE: If you
are a person who suffers with chronic viral infection while at the same time
dealing with autoimmune disorder, ask your health professional about this
product. This product is not recommended for pregnent women.
*These statements have
not been evaluated by the Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
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Features
- BioProtein+Plus has been used for Immune Support, Colds, Flu, Hepatitis
- C, and other Viral Infections. Results reported by customers may reduce
- the side effects of Chemotherapy and Radiation treatment for cancer.
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